Publications
2026
Kwon O, La H, Yoo S, Lee H, Lee H, Lim H, Park C, Han DW, Do J-T, Song H, et al. Integrative Analysis Reveals Conserved R-Loop Features in Mouse Embryonic Stem Cells. Epigenomes. 2026; 10(1):16. https://doi.org/10.3390/epigenomes10010016
Lim H, Kwon O, La H, Lee H, Lee H, Do JT, Song H, Choi Y, Hong K. INO80 regulates promoter-associated R-loops to coordinate transcription and maintain genome stability in embryonic stem cells. Biol Res. 2026 Jan 3;59(1):7. doi: 10.1186/s40659-025-00666-7. PMID: 41484646; PMCID: PMC12865974.
2025
Park C, Choi Y, Yoo S, La H, Hong K. Analysis of DNA methylation changes following Cfp1 knockout in mouse spermatocytes. Anim Biosci. 2025 Aug;38(8):1570-1579. doi: 10.5713/ab.24.0807. Epub 2025 Feb 27. PMID: 40045604; PMCID: PMC12229914.
2024
Lee H, Han DW, Yoo S, Kwon O, La H, Park C, Lee H, Kang K, Uhm SJ, Song H, Do JT, Choi Y, Hong K. RNA helicase DEAD-box-5 is involved in R-loop dynamics of preimplantation embryos. Anim Biosci. 2024 Jun;37(6):1021-1030. doi: 10.5713/ab.23.0401. Epub 2024 Feb 22. PMID: 38419548; PMCID: PMC11065950.
Lee H, Han DW, La H, Park C, Kang K, Kwon O, Uhm SJ, Song H, Do JT, Choi Y, Hong K. DOT1-like histone lysine methyltransferase is critical for adult vessel maintenance and functions. Anim Biosci. 2024 Sep;37(9):1635-1643. doi: 10.5713/ab.23.0402. Epub 2024 Apr 24. PMID: 38665093; PMCID: PMC11366529.
2023
Yoo H, La H, Park C, Yoo S, Lee H, Song H, Do JT, Choi Y and Hong K. Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome. Front. Cell Dev. Biol. 2023 Jun 11:1176115. doi: 10.3389/fcell.2023.1176115
Thang NX, Han DW, Park C, Lee H, La H, Yoo S, Lee H, Uhm SJ, Song H, Do JT, Park KS, Choi Y, Hong K. INO80 function is required for mouse mammary gland development, but mutation alone may be insufficient for breast cancer. Front Cell Dev Biol. 2023 Nov 1;11:1253274. doi: 10.3389/fcell.2023.1253274. PMID: 38020889; PMCID: PMC10646318.
2022
Thang NX, Yoo S, La H, Lee H, Park C, Park KS, Hong K. Epigenetic Factors as Etiological Agents, Diagnostic Markers, and Therapeutic Targets for Luminal Breast Cancer. Biomedicines. 2022 Mar 23;10(4):748. doi: 10.3390/biomedicines10040748. PMID: 35453496; PMCID: PMC9031900.
La H, Yoo H, Park YB, Thang NX, Park C, Yoo S, Lee H, Choi Y, Song H, Do JT, Hong K. Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development. Cells. 2022 May 19;11(10):1692. doi: 10.3390/cells11101692. PMID: 35626729; PMCID: PMC9139870.
Ki BS, Shim SH, Park C, Yoo H, La H, Lee OH, Kwon Y, Skalnik DG, Okada Y, Yoon HG, Kim JH, Hong K, Choi Y. Epigenetic regulator Cfp1 safeguards male meiotic progression by regulating meiotic gene expression. Exp Mol Med. 2022 Aug;54(8):1098-1108. doi: 10.1038/s12276-022-00813-0. Epub 2022 Aug 2. PMID: 35918532; PMCID: PMC9440128.
Lee H, You SY, Han DW, La H, Park C, Yoo S, Kang K, Kang MH, Choi Y, Hong K. Dynamic Change of R-Loop Implicates in the Regulation of Zygotic Genome Activation in Mouse. Int J Mol Sci. 2022 Nov 18;23(22):14345. doi: 10.3390/ijms232214345. PMID: 36430821; PMCID: PMC9699122.
Yoo S, Lee EJ, Thang NX, La H, Lee H, Park C, Han DW, Uhm SJ, Song H, Do JT, Choi Y, Hong K. INO80 Is Required for the Cell Cycle Control, Survival, and Differentiation of Mouse ESCs by Transcriptional Regulation. Int J Mol Sci. 2022 Dec 6;23(23):15402. doi: 10.3390/ijms232315402. PMID: 36499727; PMCID: PMC9740483.
2021
La H, Yoo H, Lee EJ, Thang NX, Choi HJ, Oh J, Park JH, Hong K. Insights from the Applications of Single-Cell Transcriptomic Analysis in Germ Cell Development and Reproductive Medicine. Int J Mol Sci. 2021 Jan 15;22(2):823. doi: 10.3390/ijms22020823. PMID: 33467661; PMCID: PMC7829788.
2020
Yoo H, La H, Lee EJ, Choi HJ, Oh J, Thang NX, Hong K. ATP-Dependent Chromatin Remodeler CHD9 Controls the Proliferation of Embryonic Stem Cells in a Cell Culture Condition-Dependent Manner. Biology (Basel). 2020 Nov 27;9(12):428. doi: 10.3390/biology9120428. PMID: 33261017; PMCID: PMC7760864.
Gurunathan S, Jeyaraj M, La H, Yoo H, Choi Y, Do JT, Park C, Kim JH, Hong K. Anisotropic Platinum Nanoparticle-Induced Cytotoxicity, Apoptosis, Inflammatory Response, and Transcriptomic and Molecular Pathways in Human Acute Monocytic Leukemia Cells. Int J Mol Sci. 2020 Jan 9;21(2):440. doi: 10.3390/ijms21020440. PMID: 31936679; PMCID: PMC7014054.
Yoo H, Lee YJ, Park C, Son D, Choi DY, Park JH, Choi HJ, La HW, Choi YJ, Moon EH, Saur D, Chung HM, Song H, Do JT, Jang H, Lee DR, Park C, Lee OH, Cho SG, Hong SH, Kong G, Kim JH, Choi Y, Hong K. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020 Jan 6;11(1):14. doi: 10.1038/s41419-019-2201-1. PMID: 31908356; PMCID: PMC6944698.
2019
Gurunathan S, Arsalan Iqbal M, Qasim M, Park CH, Yoo H, Hwang JH, Uhm SJ, Song H, Park C, Do JT, Choi Y, Kim JH, Hong K. Evaluation of Graphene Oxide Induced Cellular Toxicity and Transcriptome Analysis in Human Embryonic Kidney Cells. Nanomaterials (Basel). 2019 Jul 2;9(7):969. doi: 10.3390/nano9070969. PMID: 31269699; PMCID: PMC6669460.
Gurunathan S, Qasim M, Park CH, Arsalan Iqbal M, Yoo H, Hwang JH, Uhm SJ, Song H, Park C, Choi Y, Kim JH, Hong K. Cytotoxicity and Transcriptomic Analyses of Biogenic Palladium Nanoparticles in Human Ovarian Cancer Cells (SKOV3). Nanomaterials (Basel). 2019 May 22;9(5):787. doi: 10.3390/nano9050787. PMID: 31121951; PMCID: PMC6566439.
2018
Gurunathan S, Qasim M, Park C, Yoo H, Choi DY, Song H, Park C, Kim JH, Hong K. Cytotoxicity and Transcriptomic Analysis of Silver Nanoparticles in Mouse Embryonic Fibroblast Cells. Int J Mol Sci. 2018 Nov 16;19(11):3618. doi: 10.3390/ijms19113618. PMID: 30453526; PMCID: PMC6275036.
Hong K. Emerging function of N6-methyladenosine in cancer. Oncol Lett. 2018 Nov;16(5):5519-5524. doi: 10.3892/ol.2018.9395. Epub 2018 Sep 4. PMID: 30344705; PMCID: PMC6176263.
Gurunathan S, Qasim M, Park C, Yoo H, Kim JH, Hong K. Cytotoxic Potential and Molecular Pathway Analysis of Silver Nanoparticles in Human Colon Cancer Cells HCT116. Int J Mol Sci. 2018 Aug 2;19(8):2269. doi: 10.3390/ijms19082269. PMID: 30072642; PMCID: PMC6121495.
Hong K, Choi Y. Role of estrogen and RAS signaling in repeated implantation failure. BMB Rep. 2018 May;51(5):225-229. doi: 10.5483/bmbrep.2018.51.5.045. PMID: 29519295; PMCID: PMC5988576.
2016
Yoo H, Son D, Jang YJ, Hong K. Indispensable role for mouse ELP3 in embryonic stem cell maintenance and early development. Biochem Biophys Res Commun. 2016 Sep 16;478(2):631-6. doi: 10.1016/j.bbrc.2016.07.120. Epub 2016 Jul 29. PMID: 27476491.
Yoo H, Son D, Lee YJ, Hong K. Mouse JMJD4 is dispensable for embryogenesis. Mol Reprod Dev. 2016 Jul;83(7):588-93. doi: 10.1002/mrd.22654. Epub 2016 May 16. PMID: 27147518.
Hong K. Emerging function of N6-methyladenosine in cancer. Oncol Lett. 2018 Nov;16(5):5519-5524. doi: 10.3892/ol.2018.9395. Epub 2018 Sep 4. PMID: 30344705; PMCID: PMC6176263.
2015
Hong, K. Cellular reprogramming and its application in regenerative medicine. Tissue Eng Regen Med 12, 80–89 (2015). https://doi.org/10.1007/s13770-014-0099-3
Hong, K., Kim, YJ. & Choi, Y. Function of TET proteins in germ cell reprogramming. Genes Genom 37, 223–229 (2015). https://doi.org/10.1007/s13258-014-0254-1
2013
Han C, Hong KH, Kim YH, Kim MJ, Song C, Kim MJ, Kim SJ, Raizada MK, Oh SP. SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension. Hypertension. 2013 May;61(5):1044-52. doi: 10.1161/HYPERTENSIONAHA.111.199158. Epub 2013 Mar 11. PMID: 23478097; PMCID: PMC3740527.
2012
Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y. Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7. doi: 10.1038/nature11709. Epub 2012 Nov 14. PMID: 23151479; PMCID: PMC3528851.
2008
Hong KH, Lee YJ, Lee E, Park SO, Han C, Beppu H, Li E, Raizada MK, Bloch KD, Oh SP. Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation. 2008 Aug 12;118(7):722-30. doi: 10.1161/CIRCULATIONAHA.107.736801. Epub 2008 Jul 28. PMID: 18663089; PMCID: PMC3920834.
2007
Hong KH, Seki T, Oh SP. Activin receptor-like kinase 1 is essential for placental vascular development in mice. Lab Invest. 2007 Jul;87(7):670-9. doi: 10.1038/labinvest.3700560. Epub 2007 May 28. PMID: 17530030.